Testicular feminization: Expression in sex skin fibroblast culture
نویسندگان
چکیده
منابع مشابه
Incomplete testicular feminization syndrome.
A three and half year old girl presented to us with bilateral symmetrical swellings in the upper part of each labium majus. These were noted by her mother at birth. There was no history of any case of abnormal genitalia or inguinal hernia in her maternal aunts. Neither was there any record of intake of drugs like alcohol, hydantoins or cimetidine by the mother during pregnan On physical examina...
متن کاملTesticular Feminization Syndrome
Testicular feminization syndrome (TFS) represents a well-defined form of male pseudohermaphroditism. The patients are of female legal sex. The habitus is completely and often attractively feminine, with well-developed breasts. There is absence of axillary and pubic hair. The external genitalia are female but with a blind vagina. At laparotomy the uterus and Fallopian tubes are found to be absen...
متن کاملAndrogen insensitivity syndrome (testicular feminization).
Androgen insensitivity (testicular feminization) syndrome is a rare inherited form of male pseudohermaphroditism that occurs in phenotypically normal women with adequate breast development, normal external genitalia, a vagina of variable depth, absent uterus, and sparse or absent pubic hair and axillary hair. These patients have male karyotype (XY) and negative sex chromatin. The gonad (undesce...
متن کاملX-inactivation pattern in the epididymis of sex-reversed mice heterozygous for testicular feminization.
Female mice heterozygous for testicular feminization were sex-reversed by means of the autosomal sex reversal mutation {Sxr). Due to X-inactivation, the blastemata for male sex organs in these animals are composed of a mixture of cells, carrying either the wildtype X chromosome or the X chromosome affected with Tfm in an active state. Thus, the two types of cells are sensitive to androgens or i...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1971
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197108000-00213